Every year peptic ulcer disease PUD affects 4 milion people around the world [ 1 ]. More than half of the cases are female and they are usually older and have more comorbidities than their male counterparts [ 6 ]. Main etiologic factors include use of non-steroidal anti-inflammatory drugs NSAIDs , steroids, smoking, Helicobacter pylori and a diet high in salt [ 3 , 7 ]. All these factors have in common that they affect acid secretion in the gastric mucosa. Defining the exact etiological factor in any given patient may often be difficult, as more than one risk factor may be present and they tend to interact [ 8 ].
Perforated ulcer - Wikipedia
NCBI Bookshelf. Kamel ; Sebastiano Cassaro. Kamel 3 ; Sebastiano Cassaro 4. Perforation of the stomach is a full-thickness injury of the wall of the organ.
Diagnosis and treatment of perforated or bleeding peptic ulcers: 2013 WSES position paper
A year-old woman was admitted with a complaint of a constant dull aching pain in the epigastrium for 4 days, with subsequent worsening and generalization of the pain. Clinically the abdomen was tender all over with board-like rigidity. Chest radiography revealed pneumoperitoneum and a decision was made to explore the patient. During laparotomy we found mild peritoneal collection with no perforation in the anterior surface of the stomach, duodenum, or the entire gastrointestinal tract. After opening the gastrocolic omentum, we found a large perforation of the posterior wall of the stomach.
A perforated ulcer is a condition in which an untreated ulcer can burn through the wall of the stomach or other areas of the gastrointestinal tract , allowing digestive juices and food to leak into the abdominal cavity. Treatment generally requires immediate surgery. This is in fact one of the very few occasions in modern times where surgery is undertaken to treat an ulcer. The first symptom of a perforated peptic ulcer is usually sudden, severe, sharp pain in the abdomen.